Zovirax Cold Sore Cream is not recommended for use in immunocompromised patients. Such patients must be advised to consult a physician concerning the treatment of any infection.Adults and children:Zovirax Cold Sore Cream should be applied five times daily at approximately four hourly intervals, omitting the night time application. Zovirax Cold Sore Cream should be applied to the lesions or impending lesions as soon as possible, preferably during the earliest stages (prodrome or erythema). Treatment can also be started during the later (papule or blister) stages. Treatment should be continued for at least 4 days. If healing has not occurred, treatment may be continued for up to 10 days. If lesions are still present after 10 days, users should be advised to consult a doctor. Users should wash their hands before and after applying the cream, and avoid unnecessary rubbing of the lesions or touching them with a towel, to avoid aggravating or transferring the infection.Zovirax Cold Sore cream should only be used on cold sores on the lips and face. It is not recommended for application to mucous membranes, such as in the mouth or eye and must not be used to treat genital herpes.Particular care should be taken to avoid contact with eye. People with particularly severe recurrent herpes labialis should be encouraged to seek medical advice.Cold sore sufferers should be advised to avoid transmitting the virus, particularly when active lesions are present.