Levitra is manufactured by Bayer Pharmaceuticals and contains the active ingredient Vardenafil. It is supplied in 2.5mg, 5mg, 10mg and 20mg formulations. It is used in the treatment of erectile disfunction. It is a prescription only medicine and as such can only be acquired with a valid prescription or via an online consultation service.
Always take Levitra exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. You should not take Levitra more than once a day. You should take Levitra at least 25-60 minutes before you plan to have sex. Swallow the tablet whole with a glass of water. If you have the impression that the effect of Levitra is too strong or too weak, talk to your doctor or pharmacist. Levitra will only help you to get an erection if you are sexually stimulated. The amount of time Levitra takes to work varies from person to person, but it normally takes around 25-60 minutes. If Levitra does not help you to get an erection, or if your erection does not last long enough for you to complete sexual intercourse you should tell your doctor. You should not use Levitra more than once a day. If you take more Levitra than you should: you may experience an increase in side effects and their severity. You should not take more tablets than your doctor tells you to.
The co-administration of vardenafil with nitrates or nitric oxide donors (such as amyl nitrite) in any form is contraindicated.
Levitra is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous phosphodiesterase 5 (PDE5) inhibitor exposure.
Medicinal products for the treatment of erectile dysfunction should generally not be used in men for whom sexual activity is inadvisable (e.g. patients with severe cardiovascular disorders such as unstable angina or severe cardiac failure [New York Heart Association III or IV]).
The safety of vardenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated until further information is available:
- severe hepatic impairment (Child-Pugh C),
- end stage renal disease requiring dialysis,
- hypotension (blood pressure <90/50 mmHg),
- recent history of stroke or myocardial infarction (within the last 6 months),
- unstable angina and known hereditary retinal degenerative disorders such as retinitis pigmentosa.
Concomitant use of vardenafil with the potent CYP3A4 inhibitors ketoconazole and itraconazole (oral form) is contraindicated in men older than 75 years.
Concomitant use of vardenafil with HIV protease inhibitors such as ritonavir and indinavir is contraindicated, as they are very potent inhibitors of CYP3A4.